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Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling

Neutrophil elastase (NE) is a neutrophil-derived serine proteinase with specificity for a broad range of substrates. NE has been reported to be associated with the pathogenesis of several conditions, particularly that of pulmonary diseases. Previous studies have shown that NE can cleave the pro-myel...

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Detalles Bibliográficos
Autores principales: YANG, RONG, ZHONG, LIANG, YANG, XIAO-QUN, JIANG, KAI-LING, LI, LIU, SONG, HAO, LIU, BEI-ZHONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838072/
https://www.ncbi.nlm.nih.gov/pubmed/27035679
http://dx.doi.org/10.3892/mmr.2016.5051