S-Adenosylmethionine suppresses the expression of Smad3/4 in activated human hepatic stellate cells via Rac1 promoter methylation

The aim of the present study was to investigate whether S-adenosylmethionine (SAM) was able to suppress activated human hepatic stellate cells (HSCs). Human LX-2 HSCs were cultured with SAM or NSC23766, and were transfected with plasmids encoding ras-related C3 botulinum toxin substrate 1 (Rac1) pro...

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Detalles Bibliográficos
Autores principales: BIAN, KANGQI, ZHANG, FENG, WANG, TINGTING, ZOU, XIAOPING, DUAN, XUHONG, CHEN, GUANGXIA, ZHUGE, YUZHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838126/
https://www.ncbi.nlm.nih.gov/pubmed/26986629
http://dx.doi.org/10.3892/mmr.2016.4997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838126/
https://www.ncbi.nlm.nih.gov/pubmed/26986629
http://dx.doi.org/10.3892/mmr.2016.4997

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