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Inhibition of mTOR signaling protects photoreceptor cells against serum deprivation by reducing oxidative stress and inducing G(2)/M cell cycle arrest

The mammalian target of rapamycin (mTOR) pathway is a crucial cellular signaling hub, which integrates internal and external cues to modulate the cell cycle, protein synthesis and metabolism. The present study hypothesized that inhibiting mTOR signaling may induce cells to enter lower and more stabl...

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Detalles Bibliográficos
Autores principales: FAN, BIN, LI, FU-QAING, SONG, JING-YAO, CHEN, XU, LI, GUANG-YU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838145/
https://www.ncbi.nlm.nih.gov/pubmed/27035647
http://dx.doi.org/10.3892/mmr.2016.5011