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The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy

Background: Angiotensin converting enzyme inhibitors (ACEi) are the current standard of care treatment for cardiac dysfunction in Duchenne muscular dystrophy patients. We previously showed treatment with an ACEi plus mineralocorticoid receptor (MR) antagonist improves limb and respiratory skeletal m...

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Detalles Bibliográficos
Autores principales: Lowe, Jeovanna, Wodarcyk, Andrew J., Floyd, Kyle T., Rastogi, Neha, Schultz, Eric J., Swager, Sarah A., Chadwick, Jessica A., Tran, Tam, Raman, Subha V., Janssen, Paul M.L., Rafael-Fortney, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838202/
https://www.ncbi.nlm.nih.gov/pubmed/27110493
http://dx.doi.org/10.3233/JND-150099