A perisinusoidal niche for extramedullary haematopoiesis in the spleen

Haematopoietic stresses mobilize haematopoietic stem cells (HSCs) from the bone marrow to the spleen and induce extramedullary haematopoiesis (EMH). However, the cellular nature of the EMH niche is unknown. Here, we assessed the sources of the key niche factors, SCF and CXCL12, in the mouse spleen a...

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Detalles Bibliográficos
Autores principales: Inra, Christopher N., Zhou, Bo O., Acar, Melih, Murphy, Malea M., Richardson, James, Zhao, Zhiyu, Morrison, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838203/
https://www.ncbi.nlm.nih.gov/pubmed/26570997
http://dx.doi.org/10.1038/nature15530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838203/
https://www.ncbi.nlm.nih.gov/pubmed/26570997
http://dx.doi.org/10.1038/nature15530

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