Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer Genomics

Retroviruses have been foundational in cancer research since early studies identified proto-oncogenes as targets for insertional mutagenesis. Integration of murine gamma-retroviruses into the host genome favours promoters and enhancers and entails interaction of viral integrase with host BET/bromodo...

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Detalles Bibliográficos
Autores principales: Gilroy, Kathryn L., Terry, Anne, Naseer, Asif, de Ridder, Jeroen, Allahyar, Amin, Wang, Weiwei, Carpenter, Eric, Mason, Andrew, Wong, Gane K-S., Cameron, Ewan R., Kilbey, Anna, Neil, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838236/
https://www.ncbi.nlm.nih.gov/pubmed/27097319
http://dx.doi.org/10.1371/journal.pone.0154070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838236/
https://www.ncbi.nlm.nih.gov/pubmed/27097319
http://dx.doi.org/10.1371/journal.pone.0154070

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