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Beta-Adrenoceptor Stimulation Reveals Ca(2+) Waves and Sarcoplasmic Reticulum Ca(2+) Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure
Abnormal cellular Ca(2+) handling contributes to both contractile dysfunction and arrhythmias in heart failure. Reduced Ca(2+) transient amplitude due to decreased sarcoplasmic reticulum Ca(2+) content is a common finding in heart failure models. However, heart failure models also show increased pro...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838269/ https://www.ncbi.nlm.nih.gov/pubmed/27096943 http://dx.doi.org/10.1371/journal.pone.0153887 |