Diminished COX-2/PGE(2)-Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial Cells

Glucose-6-phosphate dehydrogenase (G6PD) provides the reducing agent NADPH to meet the cellular needs for reductive biosynthesis and the maintenance of redox homeostasis. G6PD-deficient cells experience a high level of oxidative stress and an increased susceptibility to viral infections. Cyclooxygen...

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Detalles Bibliográficos
Autores principales: Lin, Hsin-Ru, Wu, Yi-Hsuan, Yen, Wei-Chen, Yang, Chuen-Mao, Chiu, Daniel Tsun-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838297/
https://www.ncbi.nlm.nih.gov/pubmed/27097228
http://dx.doi.org/10.1371/journal.pone.0153462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838297/
https://www.ncbi.nlm.nih.gov/pubmed/27097228
http://dx.doi.org/10.1371/journal.pone.0153462

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