Cargando…

Diminished COX-2/PGE(2)-Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial Cells

Glucose-6-phosphate dehydrogenase (G6PD) provides the reducing agent NADPH to meet the cellular needs for reductive biosynthesis and the maintenance of redox homeostasis. G6PD-deficient cells experience a high level of oxidative stress and an increased susceptibility to viral infections. Cyclooxygen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Hsin-Ru, Wu, Yi-Hsuan, Yen, Wei-Chen, Yang, Chuen-Mao, Chiu, Daniel Tsun-Yee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838297/ https://www.ncbi.nlm.nih.gov/pubmed/27097228 http://dx.doi.org/10.1371/journal.pone.0153462

Ejemplares similares

Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling
por: Yen, Wei-Chen, et al.
Publicado: (2019)

Targeting COX-2/PGE(2) Pathway in HIPK2 Knockdown Cancer Cells: Impact on Dendritic Cell Maturation
por: Garufi, Alessia, et al.
Publicado: (2012)

COX-2-PGE(2)-EPs in gynecological cancers
por: Ye, Yao, et al.
Publicado: (2020)

Up-regulation of COX-2/PGE(2) by endothelin-1 via MAPK-dependent NF-κB pathway in mouse brain microvascular endothelial cells
por: Lin, Chih-Chung, et al.
Publicado: (2013)

Thrombin Induces COX-2 and PGE(2) Expression via PAR1/PKCalpha/MAPK-Dependent NF-kappaB Activation in Human Tracheal Smooth Muscle Cells
por: Yang, Chien-Chung, et al.
Publicado: (2022)

Regulated Expression of PTPRJ by COX-2/PGE(2) Axis in Endothelial Cells
por: Xu, Xiaobing, et al.
Publicado: (2014)

Pleiotropic effects of the COX-2/PGE2 axis in the glioblastoma tumor microenvironment
por: Dean, Phillip T., et al.
Publicado: (2023)

A p38 MAPK-Mediated Alteration of COX-2/PGE(2) Regulates Immunomodulatory Properties in Human Mesenchymal Stem Cell Aging
por: Yu, Kyung-Rok, et al.
Publicado: (2014)

Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia
por: Xia, Q, et al.
Publicado: (2015)

Formononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE(2) expression
por: Wang, Huiqiang, et al.
Publicado: (2015)

IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
por: Li, Yongkui, et al.
Publicado: (2018)

Role of COX-2/PGE2 Mediated Inflammation in Oral Squamous Cell Carcinoma
por: Nasry, Walaa Hamed Shaker, et al.
Publicado: (2018)

Improving VEGF-targeted therapies through inhibition of COX-2/PGE(2) signaling
por: Xu, Lihong, et al.
Publicado: (2014)

COX2 regulates senescence secretome composition and senescence surveillance through PGE(2)
por: Gonçalves, Susana, et al.
Publicado: (2021)

Dedifferentiation of Human Cardiac Myofibroblasts Is Independent of Activation of COX-2/PGE(2) Pathway
por: Luu, Vy Tran, et al.
Publicado: (2022)

COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma
por: Qi, Lu, et al.
Publicado: (2023)

Correction: A p38 MAPK-Mediated Alteration of COX-2/PGE(2) Regulates Immunomodulatory Properties in Human Mesenchymal Stem Cell Aging
Publicado: (2014)

Yersinia pseudotuberculosis YopJ Limits Macrophage Response by Downregulating COX-2-Mediated Biosynthesis of PGE2 in a MAPK/ERK-Dependent Manner
por: Sheppe, Austin E. F., et al.
Publicado: (2021)

Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B
por: Xu, Feng, et al.
Publicado: (2008)

Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer
por: Bu, Xianmin, et al.
Publicado: (2011)

Involvement of COX-2/PGE(2) signalling in hypoxia-induced angiogenic response in endothelial cells
por: Zhao, Lixing, et al.
Publicado: (2012)

Correction to: IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
por: Li, Yongkui, et al.
Publicado: (2020)

The Role of COX-2 and PGE2 in the Regulation of Immunomodulation and Other Functions of Mesenchymal Stromal Cells
por: Kulesza, Agnieszka, et al.
Publicado: (2023)

Growth and adherence of Staphylococcus aureus were enhanced through the PGE(2) produced by the activated COX-2/PGE(2) pathway of infected oral epithelial cells
por: Wang, Yuxia, et al.
Publicado: (2017)

NDRG2 Controls COX-2/PGE(2)-Mediated Breast Cancer Cell Migration and Invasion
por: Kim, Myung-Jin, et al.
Publicado: (2014)

Upregulation of COX-2 and PGE(2) Induced by TNF-α Mediated Through TNFR1/MitoROS/PKCα/P38 MAPK, JNK1/2/FoxO1 Cascade in Human Cardiac Fibroblasts
por: Yang, Chuen-Mao, et al.
Publicado: (2021)

Palmitate-Triggered COX2/PGE2-Related Hyperinflammation in Dual-Stressed PdL Fibroblasts Is Mediated by Repressive H3K27 Trimethylation
por: Schuldt, Lisa, et al.
Publicado: (2022)

Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE(2 )in primary rat microglia
por: Schlachetzki, Johannes CM, et al.
Publicado: (2010)

Activation of COX-2/PGE(2) Promotes Sapovirus Replication via the Inhibition of Nitric Oxide Production
por: Alfajaro, Mia Madel, et al.
Publicado: (2017)

Atorvastatin attenuates plaque vulnerability by downregulation of EMMPRIN expression via COX-2/PGE2 pathway
por: Liang, Xing, et al.
Publicado: (2017)

Mesenchymal stem cells inhibited the differentiation of MDSCs via COX2/PGE2 in experimental sialadenitis
por: Qi, Jingjing, et al.
Publicado: (2020)

Targeting of the COX-2/PGE2 axis enhances the antitumor activity of T7 peptide in vitro and in vivo
por: Yang, Jianrong, et al.
Publicado: (2021)

Glucose 6-phosphate dehydrogenase knockdown enhances IL-8 expression in HepG2 cells via oxidative stress and NF-κB signaling pathway
por: Yang, Hung-Chi, et al.
Publicado: (2015)

COX-2/PGE2: molecular ambassadors of Kaposi's sarcoma-associated herpes virus oncoprotein-v-FLIP
por: Sharma-Walia, N, et al.
Publicado: (2012)

Key role of the positive feedback between PGE(2) and COX2 in the biology of myeloid-derived suppressor cells
por: Obermajer, Nataŝa, et al.
Publicado: (2012)

COX-2-derived PGE(2) triggers hyperplastic renin expression and hyperreninemia in aldosterone synthase-deficient mice
por: Karger, Christian, et al.
Publicado: (2018)

Feline calicivirus- and murine norovirus-induced COX-2/PGE(2) signaling pathway has proviral effects
por: Alfajaro, Mia Madel, et al.
Publicado: (2018)

Resveratrol treatment inhibits acute pharyngitis in the mice model through inhibition of PGE2/COX-2 expression
por: Yu, Zhaoyan, et al.
Publicado: (2018)

Regulation of Matrix Metalloproteinase-2 Activity by COX-2-PGE2-pAKT Axis Promotes Angiogenesis in Endometriosis
por: Jana, Sayantan, et al.
Publicado: (2016)

The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE(2) from Epithelial Cells
por: Lin, Yen-Ju, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b3523gvhk7rrqg7kq0c50kpr68