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Single-Patient Molecular Testing with NanoString nCounter Data Using a Reference-Based Strategy for Batch Effect Correction

A major weakness in many high-throughput genomic studies is the lack of consideration of a clinical environment where one patient at a time must be evaluated. We examined generalizable and platform-specific sources of variation from NanoString gene expression data on both ovarian cancer and Hodgkin...

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Detalles Bibliográficos
Autores principales: Talhouk, Aline, Kommoss, Stefan, Mackenzie, Robertson, Cheung, Martin, Leung, Samuel, Chiu, Derek S., Kalloger, Steve E., Huntsman, David G., Chen, Stephanie, Intermaggio, Maria, Gronwald, Jacek, Chan, Fong C., Ramus, Susan J., Steidl, Christian, Scott, David W., Anglesio, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838303/
https://www.ncbi.nlm.nih.gov/pubmed/27096160
http://dx.doi.org/10.1371/journal.pone.0153844