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The conditional KO approach: Cre/Lox technology in human neurons

The use of human pluripotent stem cells to model human diseases has become a new standard in biomedical sciences. To this end, patient-derived somatic cells are studied in vitro to mimic human pathological conditions. Here, we describe an alternative experimental strategy, the ‘conditional KO approa...

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Detalles Bibliográficos
Autores principales: Patzke, Christopher, Südhof, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838317/
https://www.ncbi.nlm.nih.gov/pubmed/27141410
http://dx.doi.org/10.1080/21675511.2015.1131884