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The conditional KO approach: Cre/Lox technology in human neurons
The use of human pluripotent stem cells to model human diseases has become a new standard in biomedical sciences. To this end, patient-derived somatic cells are studied in vitro to mimic human pathological conditions. Here, we describe an alternative experimental strategy, the ‘conditional KO approa...
Autores principales: | Patzke, Christopher, Südhof, Thomas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838317/ https://www.ncbi.nlm.nih.gov/pubmed/27141410 http://dx.doi.org/10.1080/21675511.2015.1131884 |
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