Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration

The mechanical properties of the cell nucleus change to allow cells to migrate, but how chromatin modifications contribute to nuclear deformability has not been defined. Here, we demonstrate that a major factor in this process involves epigenetic changes that underpin nuclear structure. We investiga...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaohong, Cook, Peter C., Zindy, Egor, Williams, Craig J., Jowitt, Thomas A., Streuli, Charles H., MacDonald, Andrew S., Redondo-Muñoz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838336/
https://www.ncbi.nlm.nih.gov/pubmed/26657637
http://dx.doi.org/10.1093/nar/gkv1348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838336/
https://www.ncbi.nlm.nih.gov/pubmed/26657637
http://dx.doi.org/10.1093/nar/gkv1348

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