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Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration
The mechanical properties of the cell nucleus change to allow cells to migrate, but how chromatin modifications contribute to nuclear deformability has not been defined. Here, we demonstrate that a major factor in this process involves epigenetic changes that underpin nuclear structure. We investiga...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838336/ https://www.ncbi.nlm.nih.gov/pubmed/26657637 http://dx.doi.org/10.1093/nar/gkv1348 |