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Enhanced sequencing coverage with digital droplet multiple displacement amplification
Sequencing small quantities of DNA is important for applications ranging from the assembly of uncultivable microbial genomes to the identification of cancer-associated mutations. To obtain sufficient quantities of DNA for sequencing, the small amount of starting material must be amplified significan...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838355/ https://www.ncbi.nlm.nih.gov/pubmed/26704978 http://dx.doi.org/10.1093/nar/gkv1493 |