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Enhanced sequencing coverage with digital droplet multiple displacement amplification

Sequencing small quantities of DNA is important for applications ranging from the assembly of uncultivable microbial genomes to the identification of cancer-associated mutations. To obtain sufficient quantities of DNA for sequencing, the small amount of starting material must be amplified significan...

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Detalles Bibliográficos
Autores principales: Sidore, Angus M., Lan, Freeman, Lim, Shaun W., Abate, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838355/
https://www.ncbi.nlm.nih.gov/pubmed/26704978
http://dx.doi.org/10.1093/nar/gkv1493