Cargando…

TopDom: an efficient and deterministic method for identifying topological domains in genomes

Genome-wide proximity ligation assays allow the identification of chromatin contacts at unprecedented resolution. Several studies reveal that mammalian chromosomes are composed of topological domains (TDs) in sub-mega base resolution, which appear to be conserved across cell types and to some extent...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Hanjun, Shi, Yi, Dai, Chao, Tjong, Harianto, Gong, Ke, Alber, Frank, Zhou, Xianghong Jasmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838359/
https://www.ncbi.nlm.nih.gov/pubmed/26704975
http://dx.doi.org/10.1093/nar/gkv1505