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FANCM interacts with PCNA to promote replication traverse of DNA interstrand crosslinks

FANCM is a highly conserved DNA remodeling enzyme that promotes the activation of the Fanconi anemia DNA repair pathway and facilitates replication traverse of DNA interstrand crosslinks. However, how FANCM interacts with the replication machinery to promote traverse remains unclear. Here, we show t...

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Detalles Bibliográficos
Autores principales: Rohleder, Florian, Huang, Jing, Xue, Yutong, Kuper, Jochen, Round, Adam, Seidman, Michael, Wang, Weidong, Kisker, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838364/
https://www.ncbi.nlm.nih.gov/pubmed/26825464
http://dx.doi.org/10.1093/nar/gkw037