Initiation on the divergent Type I cadicivirus IRES: factor requirements and interactions with the translation apparatus

Cadicivirus (CDV) is unique amongst picornaviruses in having a dicistronic genome with internal ribosomal entry sites (IRESs) preceding both open reading frames. Here, we investigated initiation on the 5′-terminal IRES. We report that the 982-nt long 5′UTR comprises 12 domains (d1-d12), five of whic...

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Detalles Bibliográficos
Autores principales: Asnani, Mukta, Pestova, Tatyana V., Hellen, Christopher U.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838371/
https://www.ncbi.nlm.nih.gov/pubmed/26873921
http://dx.doi.org/10.1093/nar/gkw074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838371/
https://www.ncbi.nlm.nih.gov/pubmed/26873921
http://dx.doi.org/10.1093/nar/gkw074

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