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Initiation on the divergent Type I cadicivirus IRES: factor requirements and interactions with the translation apparatus
Cadicivirus (CDV) is unique amongst picornaviruses in having a dicistronic genome with internal ribosomal entry sites (IRESs) preceding both open reading frames. Here, we investigated initiation on the 5′-terminal IRES. We report that the 982-nt long 5′UTR comprises 12 domains (d1-d12), five of whic...
Autores principales: | Asnani, Mukta, Pestova, Tatyana V., Hellen, Christopher U.T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838371/ https://www.ncbi.nlm.nih.gov/pubmed/26873921 http://dx.doi.org/10.1093/nar/gkw074 |
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