Cargando…

Endonuclease domain of non-LTR retrotransposons: loss-of-function mutants and modeling of the R2Bm endonuclease

Non-LTR retrotransposons are an important class of mobile elements that insert into host DNA by target-primed reverse transcription (TPRT). Non-LTR retrotransposons must bind to their mRNA, recognize and cleave their target DNA, and perform TPRT at the site of DNA cleavage. As DNA binding and cleava...

Descripción completa

Detalles Bibliográficos
Autores principales: Govindaraju, Aruna, Cortez, Jeremy D., Reveal, Brad, Christensen, Shawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838377/
https://www.ncbi.nlm.nih.gov/pubmed/26961309
http://dx.doi.org/10.1093/nar/gkw134