Global analyses of endonucleolytic cleavage in mammals reveal expanded repertoires of cleavage-inducing small RNAs and their targets

In mammals, small RNAs are important players in post-transcriptional gene regulation. While their roles in mRNA destabilization and translational repression are well appreciated, their involvement in endonucleolytic cleavage of target RNAs is poorly understood. Very few microRNAs are known to guide...

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Detalles Bibliográficos
Autores principales: Cass, Ashley A., Bahn, Jae Hoon, Lee, Jae-Hyung, Greer, Christopher, Lin, Xianzhi, Kim, Yong, Hsiao, Yun-Hua Esther, Xiao, Xinshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838385/
https://www.ncbi.nlm.nih.gov/pubmed/26975654
http://dx.doi.org/10.1093/nar/gkw164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838385/
https://www.ncbi.nlm.nih.gov/pubmed/26975654
http://dx.doi.org/10.1093/nar/gkw164

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