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Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases

DNA templates containing a set of base modifications in the major groove (5-substituted pyrimidines or 7-substituted 7-deazapurines bearing H, methyl, vinyl, ethynyl or phenyl groups) were prepared by PCR using the corresponding base-modified 2′-deoxyribonucleoside triphosphates (dNTPs). The modifie...

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Detalles Bibliográficos
Autores principales: Raindlová, Veronika, Janoušková, Martina, Slavíčková, Michaela, Perlíková, Pavla, Boháčová, Soňa, Milisavljevič, Nemanja, Šanderová, Hana, Benda, Martin, Barvík, Ivan, Krásný, Libor, Hocek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838386/
https://www.ncbi.nlm.nih.gov/pubmed/27001521
http://dx.doi.org/10.1093/nar/gkw171