PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities

Translesion synthesis (TLS) employs specialized DNA polymerases to bypass replication fork stalling lesions. PrimPol was recently identified as a TLS primase and polymerase involved in DNA damage tolerance. Here, we identify a novel PrimPol binding partner, PolDIP2, and describe how it regulates Pri...

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Detalles Bibliográficos
Autores principales: Guilliam, Thomas A., Bailey, Laura J., Brissett, Nigel C., Doherty, Aidan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838387/
https://www.ncbi.nlm.nih.gov/pubmed/26984527
http://dx.doi.org/10.1093/nar/gkw175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838387/
https://www.ncbi.nlm.nih.gov/pubmed/26984527
http://dx.doi.org/10.1093/nar/gkw175

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