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Statistical issues in trials of preexposure prophylaxis

PURPOSE OF REVIEW: We discuss selected statistical issues in the design and analysis of preexposure prophylaxis (PrEP) trials. The general principles may inform thinking for other interventions in HIV prevention. RECENT FINDINGS: To date, four different designs have been used to determine the effect...

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Detalles Bibliográficos
Autores principales: Dunn, David T., Glidden, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838412/
https://www.ncbi.nlm.nih.gov/pubmed/26545264
http://dx.doi.org/10.1097/COH.0000000000000218