Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-Review

Huntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease caused by an expanded polyglutamine (polyQ) tract in the N-terminal region of mutant huntingtin (mHtt). As a result, mHtt forms aggregates that are abundant in the nuclei and processes of neuronal cells. Althou...

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Detalles Bibliográficos
Autores principales: Zhao, Ting, Hong, Yan, Li, Xiao-Jiang, Li, Shi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838617/
https://www.ncbi.nlm.nih.gov/pubmed/27147961
http://dx.doi.org/10.3389/fnmol.2016.00027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838617/
https://www.ncbi.nlm.nih.gov/pubmed/27147961
http://dx.doi.org/10.3389/fnmol.2016.00027

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