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Functional Implications of the CLOCK 3111T/C Single-Nucleotide Polymorphism

Circadian rhythm disruptions are prominently associated with bipolar disorder (BD). Circadian rhythms are regulated by the molecular clock, a family of proteins that function together in a transcriptional–translational feedback loop. The CLOCK protein is a key transcription factor of this feedback l...

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Detalles Bibliográficos
Autores principales: Ozburn, Angela R., Purohit, Kush, Parekh, Puja K., Kaplan, Gabrielle N., Falcon, Edgardo, Mukherjee, Shibani, Cates, Hannah M., McClung, Colleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838618/
https://www.ncbi.nlm.nih.gov/pubmed/27148095
http://dx.doi.org/10.3389/fpsyt.2016.00067