Aldehyde Dehydrogenase 2 Has Cardioprotective Effects on Myocardial Ischaemia/Reperfusion Injury via Suppressing Mitophagy

Mitophagy, a selective form of autophagy, is excessively activated in myocardial ischemia/reperfusion (I/R). The study investigated whether aldehyde dehydrogenase 2 (ALDH2) exerted its cardioprotective effect by regulating mitophagy. Myocardial infarct size and apoptosis after I/R in rats were ameli...

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Detalles Bibliográficos
Autores principales: Ji, Wenqing, Wei, Shujian, Hao, Panpan, Xing, Junhui, Yuan, Qiuhuan, Wang, Jiali, Xu, Feng, Chen, Yuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838626/
https://www.ncbi.nlm.nih.gov/pubmed/27148058
http://dx.doi.org/10.3389/fphar.2016.00101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838626/
https://www.ncbi.nlm.nih.gov/pubmed/27148058
http://dx.doi.org/10.3389/fphar.2016.00101

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