PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis

Giant cell arteritis (GCA) is one of the commonest forms of vasculitis in the elderly, and may result in blindness and stroke. The pathogenesis of GCA is not understood, although environmental, infectious and genetic risk factors are implicated. One gene of interest is PTPN22, encoding lymphoid prot...

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Detalles Bibliográficos
Autores principales: Lester, Susan, Hewitt, Alex W, Ruediger, Carlee D, Bradbury, Linda, De Smit, Elisabeth, Wiese, Michael D, Black, Rachel, Harrison, Andrew, Jones, Graeme, Littlejohn, Geoffrey O, Merriman, Tony R, Shenstone, Bain, Smith, Malcolm D, Rischmueller, Maureen, Brown, Matthew A, Hill, Catherine L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Vasculitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838769/
https://www.ncbi.nlm.nih.gov/pubmed/27110387
http://dx.doi.org/10.1136/rmdopen-2016-000246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838769/
https://www.ncbi.nlm.nih.gov/pubmed/27110387
http://dx.doi.org/10.1136/rmdopen-2016-000246

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