Lycium barbarum Polysaccharides Protect against Trimethyltin Chloride-Induced Apoptosis via Sonic Hedgehog and PI3K/Akt Signaling Pathways in Mouse Neuro-2a Cells

Trimethyltin chloride (TMT) is a classic neurotoxicant that can cause severe neurodegenerative diseases. Some signaling pathways involving cell death play pivotal roles in the central nervous system. In this study, the role of Sonic Hedgehog (Shh) and PI3K/Akt pathways in TMT-induced apoptosis and p...

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Detalles Bibliográficos
Autores principales: Zhao, Wanyun, Pan, Xiaoqi, Li, Tao, Zhang, Changchun, Shi, Nian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838808/
https://www.ncbi.nlm.nih.gov/pubmed/27143997
http://dx.doi.org/10.1155/2016/9826726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838808/
https://www.ncbi.nlm.nih.gov/pubmed/27143997
http://dx.doi.org/10.1155/2016/9826726

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