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Tum/RacGAP functions as a switch activating the Pav/kinesin-6 motor

Centralspindlin is essential for central spindle and cleavage furrow formation. Drosophila centralspindlin consists of a kinesin-6 motor (Pav/kinesin-6) and a GTPase-activating protein (Tum/RacGAP). Centralspindlin localization to the central spindle is mediated by Pav/kinesin-6. While Tum/RacGAP ha...

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Detalles Bibliográficos
Autores principales: Tao, Li, Fasulo, Barbara, Warecki, Brandt, Sullivan, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838857/
https://www.ncbi.nlm.nih.gov/pubmed/27091402
http://dx.doi.org/10.1038/ncomms11182