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Yeast V-ATPase Proteolipid Ring Acts as a Large-conductance Transmembrane Protein Pore

The vacuolar H(+) -ATPase (V-ATPase) is a rotary motor enzyme that acidifies intracellular organelles and the extracellular milieu in some tissues. Besides its canonical proton-pumping function, V-ATPase’s membrane sector, V(o), has been implicated in non-canonical functions including membrane fusio...

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Detalles Bibliográficos
Autores principales: Couoh-Cardel, Sergio, Hsueh, Yi-Ching, Wilkens, Stephan, Movileanu, Liviu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838861/
https://www.ncbi.nlm.nih.gov/pubmed/27098228
http://dx.doi.org/10.1038/srep24774