From molecular interaction to acute promyelocytic leukemia: Calculating leukemogenesis and remission from endogenous molecular-cellular network

Acute promyelocytic leukemia (APL) remains the best example of a malignancy that can be cured clinically by differentiation therapy. We demonstrate that APL may emerge from a dynamical endogenous molecular-cellular network obtained from normal, non-cancerous molecular interactions such as signal tra...

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Detalles Bibliográficos
Autores principales: Yuan, Ruoshi, Zhu, Xiaomei, Radich, Jerald P., Ao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838884/
https://www.ncbi.nlm.nih.gov/pubmed/27098097
http://dx.doi.org/10.1038/srep24307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838884/
https://www.ncbi.nlm.nih.gov/pubmed/27098097
http://dx.doi.org/10.1038/srep24307

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