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Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer
Acetyl-CoA carboxylase (ACC) has crucial roles in fatty acid metabolism and is an attractive target for drug discovery against diabetes, cancer and other diseases(1–6). Saccharomyces cerevisiae ACC (ScACC) is crucial for the production of very-long-chain fatty acids and the maintenance of the nuclea...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838907/ https://www.ncbi.nlm.nih.gov/pubmed/26458104 http://dx.doi.org/10.1038/nature15375 |