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Molecular simulations of conformation change and aggregation of HIV-1 Vpr13-33 on graphene oxide

Recent experiments have reported that the fragment of viral protein R (Vpr), Vpr13-33, can assemble and change its conformation after adsorbed on graphene oxide (GO) and then reduce its cytotoxicity. This discovery is of great importance, since the mutation of Vpr13-33 can decrease the viral replica...

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Detalles Bibliográficos
Autores principales: Zeng, Songwei, Zhou, Guoquan, Guo, Jianzhong, Zhou, Feng, Chen, Junlang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838942/
https://www.ncbi.nlm.nih.gov/pubmed/27097898
http://dx.doi.org/10.1038/srep24906