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Targeting Antigens to Dec-205 on Dendritic Cells Induces Immune Protection in Experimental Colitis in Mice

The endocytotic c-type lectin receptor DEC-205 is highly expressed on immature dendritic cells. In previous studies, it was shown that antigen-targeting to DEC-205 is a useful tool for the induction of antigen-specific Foxp3(+) regulatory T cells and thereby can prevent inflammatory processes. Howev...

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Detalles Bibliográficos
Autores principales: Wadwa, Munisch, Klopfleisch, Robert, Buer, Jan, Westendorf, Astrid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Akadémiai Kiadó 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838981/
https://www.ncbi.nlm.nih.gov/pubmed/27141310
http://dx.doi.org/10.1556/1886.2015.00048