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Neonatal atypical hemolytic uremic syndrome from a factor H mutation treated with eculizumab

Background: Atypical hemolytic uremic syndrome (aHUS) results from an inherited dysregulation of the alternative complement pathway leading to thrombotic microangiopathy consisting of hemolytic anemia, thrombocytopenia, and renal injury. The complement inhibitor eculizumab is an approved treatment,...

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Detalles Bibliográficos
Autores principales: Sharma, Sheena, Pradhan, Madhura, Meyers, Kevin E.C., Le Palma, Krish, Laskin, Benjamin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839031/
https://www.ncbi.nlm.nih.gov/pubmed/25816809
http://dx.doi.org/10.5414/CN108532