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High-dose chemotherapy and autologous stem cell transplant compared with conventional chemotherapy for consolidation in newly diagnosed primary CNS lymphoma—a randomized phase III trial (MATRix)

BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a highly aggressive Non-Hodgkin lymphoma (NHL) with rising incidence over the past 30 years in immunocompetent patients. Although outcomes have improved, PCNSL is still associated with inferior prognosis compared to systemic NHL. Many qu...

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Detalles Bibliográficos
Autores principales: Schorb, Elisabeth, Finke, Juergen, Ferreri, Andrés J. M., Ihorst, Gabriele, Mikesch, Kristina, Kasenda, Benjamin, Fritsch, Kristina, Fricker, Heidi, Burger, Elvira, Grishina, Olga, Valk, Elke, Zucca, Emanuele, Illerhaus, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839072/
https://www.ncbi.nlm.nih.gov/pubmed/27098429
http://dx.doi.org/10.1186/s12885-016-2311-4