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Alcohol-related breast cancer in postmenopausal women – effect of CYP19A1, PPARG and PPARGC1A polymorphisms on female sex-hormone levels and interaction with alcohol consumption and NSAID usage in a nested case-control study and a randomised controlled trial

BACKGROUND: Alcohol consumption is associated with increased risk of breast cancer (BC), and the underlying mechanism is thought to be sex-hormone driven. In vitro and observational studies suggest a mechanism involving peroxisome proliferator-activated receptor gamma (PPARγ) in a complex with perox...

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Detalles Bibliográficos
Autores principales: Kopp, Tine Iskov, Jensen, Ditte Marie, Ravn-Haren, Gitte, Cohen, Arieh, Sommer, Helle Molgaard, Dragsted, Lars Ove, Tjonneland, Anne, Hougaard, David Michael, Vogel, Ulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839098/
https://www.ncbi.nlm.nih.gov/pubmed/27102200
http://dx.doi.org/10.1186/s12885-016-2317-y