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Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication

Diabetes is associated with loss of functional pancreatic β-cells, and restoration of β-cells is a major goal for regenerative therapies. Endogenous regeneration of β-cells via β-cell replication has the potential to restore cellular mass; however, pharmacological agents that promote regeneration or...

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Detalles Bibliográficos
Autores principales: Dhawan, Sangeeta, Dirice, Ercument, Kulkarni, Rohit N., Bhushan, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839200/
https://www.ncbi.nlm.nih.gov/pubmed/26936960
http://dx.doi.org/10.2337/db15-1331