Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups

α-Helix proteomimetics represent an emerging class of ligands that can be used to inhibit an array of helix mediated protein–protein interactions. Within this class of inhibitor, aromatic oligobenzamide foldamers have been widely and successfully used. This manuscript describes alternative syntheses...

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Detalles Bibliográficos
Autores principales: Burslem, George M., Kyle, Hannah F., Prabhakaran, Panchami, Breeze, Alexander L., Edwards, Thomas A., Warriner, Stuart L., Nelson, Adam, Wilson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839272/
https://www.ncbi.nlm.nih.gov/pubmed/27005701
http://dx.doi.org/10.1039/c6ob00078a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839272/
https://www.ncbi.nlm.nih.gov/pubmed/27005701
http://dx.doi.org/10.1039/c6ob00078a

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