Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligos

Copy number variations have been frequently associated with developmental delay, intellectual disability, and autism spectrum disorders(1). MECP2 duplication syndrome is one of the most common genomic rearrangements in males(2) and is characterized by autism, intellectual disability, motor dysfuncti...

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Detalles Bibliográficos
Autores principales: Sztainberg, Yehezkel, Chen, Hong-mei, Swann, John W., Hao, Shuang, Tang, Bin, Wu, Zhenyu, Tang, Jianrong, Wan, Ying-Wooi, Liu, Zhandong, Rigo, Frank, Zoghbi, Huda Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839300/
https://www.ncbi.nlm.nih.gov/pubmed/26605526
http://dx.doi.org/10.1038/nature16159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839300/
https://www.ncbi.nlm.nih.gov/pubmed/26605526
http://dx.doi.org/10.1038/nature16159

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