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Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer?

Pancreatic cancer is extremely resistant to chemo- and radiation-therapies due to its inherent genetic instability, the local immunosuppressive microenvironment and the remarkable desmoplastic stromal changes which characterize this cancer. Therefore, there is an urgent need for improvement on stand...

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Detalles Bibliográficos
Autores principales: Brunet, Laura Rosa, Hagemann, Thorsten, Gaya, Andrew, Mudan, Satvinder, Marabelle, Aurelien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839322/
https://www.ncbi.nlm.nih.gov/pubmed/27141395
http://dx.doi.org/10.1080/2162402X.2015.1112942