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Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer?
Pancreatic cancer is extremely resistant to chemo- and radiation-therapies due to its inherent genetic instability, the local immunosuppressive microenvironment and the remarkable desmoplastic stromal changes which characterize this cancer. Therefore, there is an urgent need for improvement on stand...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839322/ https://www.ncbi.nlm.nih.gov/pubmed/27141395 http://dx.doi.org/10.1080/2162402X.2015.1112942 |