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Opposing effects of immunotherapy in melanoma using multisubtype interferon-alpha – can tumor immune escape after immunotherapy accelerate disease progression?

With checkpoint inhibitors, patients with advanced melanoma display durable responses suggesting cure of disease. However, the immune system has dual roles in cancer; while the immune system may eradicate a tumor, a subtotal elimination may selectively destroy immunogenic cells driving the prolifera...

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Detalles Bibliográficos
Autores principales: Strannegård, Örjan, Thorén, Fredrik B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839365/
https://www.ncbi.nlm.nih.gov/pubmed/27141351
http://dx.doi.org/10.1080/2162402X.2015.1091147