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NKG2D- and T-cell receptor-dependent lysis of malignant glioma cell lines by human γδ T cells: Modulation by temozolomide and A disintegrin and metalloproteases 10 and 17 inhibitors

The interaction of the MHC class I-related chain molecules A and B (MICA and MICB) and UL-16 binding protein (ULBP) family members expressed on tumor cells with the corresponding NKG2D receptor triggers cytotoxic effector functions in NK cells and γδ T cells. However, as a mechanism of tumor immune...

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Detalles Bibliográficos
Autores principales: Chitadze, Guranda, Lettau, Marcus, Luecke, Stefanie, Wang, Ting, Janssen, Ottmar, Fürst, Daniel, Mytilineos, Joannis, Wesch, Daniela, Oberg, Hans-Heinrich, Held-Feindt, Janka, Kabelitz, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839372/
https://www.ncbi.nlm.nih.gov/pubmed/27141377
http://dx.doi.org/10.1080/2162402X.2015.1093276