Paclitaxel-induced epithelial damage and ectopic MMP-13 expression promotes neurotoxicity in zebrafish

Paclitaxel is a microtubule-stabilizing chemotherapeutic agent that is widely used in cancer treatment and in a number of curative and palliative regimens. Despite its beneficial effects on cancer, paclitaxel also damages healthy tissues, most prominently the peripheral sensory nervous system. The m...

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Detalles Bibliográficos
Autores principales: Lisse, Thomas S., Elias, Leah J., Pellegrini, Adriana D., Martin, Paige B., Spaulding, Emily L., Lopes, Olivia, Brochu, Elizabeth A., Carter, Erin V., Waldron, Ashley, Rieger, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2016
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839466/
https://www.ncbi.nlm.nih.gov/pubmed/27035978
http://dx.doi.org/10.1073/pnas.1525096113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839466/
https://www.ncbi.nlm.nih.gov/pubmed/27035978
http://dx.doi.org/10.1073/pnas.1525096113

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