Association of Angiopoietin-2 and Ki-67 Expression with Vascular Density and Sunitinib Response in Metastatic Renal Cell Carcinoma

The Angiopoietin-2 (Ang2, Angpt2) growth factor is a context-dependent antagonist/agonist ligand of the endothelial Tie2 receptor tyrosine kinase and known to promote tumour angiogenesis and metastasis. Angiopoietin antagonists have been tested in clinical cancer trials in combination with VEGF-base...

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Detalles Bibliográficos
Autores principales: Rautiola, Juhana, Lampinen, Anita, Mirtti, Tuomas, Ristimäki, Ari, Joensuu, Heikki, Bono, Petri, Saharinen, Pipsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839598/
https://www.ncbi.nlm.nih.gov/pubmed/27100185
http://dx.doi.org/10.1371/journal.pone.0153745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839598/
https://www.ncbi.nlm.nih.gov/pubmed/27100185
http://dx.doi.org/10.1371/journal.pone.0153745

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