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Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors

Hsa is a large, serine-rich protein of Streptococcus gordonii DL1 that mediates binding to α2-3-linked sialic acid termini of glycoproteins, including platelet glycoprotein Ibα, and erythrocyte membrane protein glycophorin A, and band 3. The binding of Hsa to platelet glycoprotein Ibα contributes to...

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Detalles Bibliográficos
Autores principales: Urano-Tashiro, Yumiko, Takahashi, Yukihiro, Oguchi, Riyo, Konishi, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839618/
https://www.ncbi.nlm.nih.gov/pubmed/27101147
http://dx.doi.org/10.1371/journal.pone.0154098