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Production of Functionally Active and Immunogenic Non-Glycosylated Protective Antigen from Bacillus anthracis in Nicotiana benthamiana by Co-Expression with Peptide-N-Glycosidase F (PNGase F) of Flavobacterium meningosepticum

Bacillus anthracis has long been considered a potential biological warfare agent, and therefore, there is a need for a safe, low-cost and highly efficient anthrax vaccine with demonstrated long-term stability for mass vaccination in case of an emergency. Many efforts have been made towards developin...

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Detalles Bibliográficos
Autores principales: Mamedov, Tarlan, Chichester, Jessica A., Jones, R. Mark, Ghosh, Ananya, Coffin, Megan V., Herschbach, Kristina, Prokhnevsky, Alexey I., Streatfield, Stephen J., Yusibov, Vidadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839623/
https://www.ncbi.nlm.nih.gov/pubmed/27101370
http://dx.doi.org/10.1371/journal.pone.0153956